Dr. Ann J Peters on the Importance of Telomeres

I recommend telomere length assessment for my paitents as a way to measure cellular aging.  This article is from Life Length. the first company in the world to make Telomere Analysis Technology (TAT), developed by Dr. Maria Blasco, current Director of the Spanish National Cancer Research Centre (CNIO), available to individuals on a commercial basis.

“Telomeres are specialized structures on the ends of chromosomes that protect them from fusions and degradation in this way ensuring cell viability. Telomere loss, however, occurs as a natural result of normal DNA replication.

  • Telomeres protect chromosomes against degradation, fusion, and rearrangements during DNA replication
  • Telomeres preserve the integrity of chromosomes by allowing the complete replication of the ends of chromosomal DNA through the activity of the enzyme telomerase
  • Telomeres facilitate the correct positioning of the chromosomes within the nucleus for replication

In mammalian cells, telomeres are composed of tandem repeats of the TTAGGG sequence that span10 to 15 kilobases and the various proteins that bind to this region.

During DNA replication, the terminal end of the telomere is not replicated resulting in the continual shortening of telomeres losing TTAGGG repeats.

The average number of base pairs lost per year varies depending upon both genetic and environmental factors.

Eventually, the telomeres shorten to a critical length resulting in chromosomal instability and loss of cell viability.”

Knowing the length of a person’s telomeres allows a better understanding and treatment for the individual’s cellular health and anti-aging process.

About Dr. Peters:  Dr. Peters medical practice is focused on anti-aging and longevity with offices in San Francisco, New York and Palm Beach.  Helping clients look, feel and live longer and better by delaying, preventing and reversing the signs and symptoms of aging. She received the most prestigious cosmopolitan education around the world.  A graduate with a medical degree from the University of Medicine and Dentistry of New Jersey (UMDNJ), she completed her medical internships and fellowships at Cornell Medical Center, New York, Harvard School of Public Health and Ospadali Galleria in Genoa, Italy.  She is a past scholar of Leopold Schlep Foundation, and the Organization of American States (OAS), New York.

Her medical affiliations include American Academy of Anti-Aging Medicine, European Academy of Quality of Life and Longevity Medicine and the International Hormone Society. Board Certified with the American Academy of Family Physicians, she is a diplomat with the American Board of Family Practice and an award-recognized physician from Harvard School of Public Health.

For more information on Dr. Peters go to http://www.mdlongevity.com



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